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| The analysis of 236 patients with drug eruption in hospital |
| DING Changling1, MA Zhenzhen1, GAO Fei1, CHENG Wenna1, ZHANG Junhua2, DING Zhaoxing1, TIAN Yuejie3 |
1 Department of Pharmacy,Binzhou Medical University Hospital,Binzhou 256603, P. R. China;
2 Binzhou Control Centre for Food and Drug;
3 Shandong Centre for Adverse Drug Reaction Monitoring |
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Abstract Objective To analyze the clinical medication,rationality of using drugs and costs of medication in hospital of patients with drug eruption in hospital and provide reference of rational drug use,prevention of drug eruption and establish phytotoxicity compensation system.Methods The aspects of patients` general data,medications,types of drug eruption,hospitalization cost and the length of hospital stay of 236 patients who were treated in hospital for drug eruption were retrospectively analyzed.Results 190 patients were causative drugs identified,including 97 cases of oral administration and 63 cases of intravenous administration.The first causative drug was antibiotics,followed by Chinese patent medicine,antipyretic-analgesic drugs and antiepileptics.221 were slight drug eruption and 15 were severe drug eruption.The average length of hospital stay was (10.75±9.56) days, and the average medical costs were (8356.50 ± 2198.45) Yuan for 236 drug eruption cases.Conclusion Rational use of drug plays an important role in the prevention of drug eruption.Therefore,medical personnel should strengthen rational drug use propaganda and establish phytotoxicity compensation system to ensure the safety of patients.
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Received: 28 December 2018
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