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| Clinical study of triple therapy for adult early necrosis of femoral head |
| CAO Heng, LIU Mingting*, SHI Hui, LI Jian, WANG Jianming, HUANG Kaiyue |
| Department of Bone and Joint Surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong, P. R. China |
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Abstract Objective To investigate the clinical effect of the triple therapy of extracorporeal shock wave combined with hyperbaric oxygen and blood circulation drugs in the treatment of adult early necrosis of femoral head, so as to provide valuable experience for clinical work.Methods Thirty patients with femoral head necrosis in the department of joint surgery were chosen. ARCO stage was Ⅰ period of 17 cases, Ⅱ period 13 cases, and patients received triple therapy treatment of extracorporeal shock wave combined with hyperbaric oxygen and blood circulation drugs. The patients were followed up for 3 months, and before the treatment and after three periods of treatment, the calculation was performed on VAS scores, Harris scores, limb medial femoral circumflex artery blood flow resistance index (RI), and the percentage of femoral head necrosis volume in overall femoral head volume.Results VAS scores and Harris scores were lower after the same stage of treatment than those before the treatment, P<0.01. Compared with those of stage I, the VAS scores of stage II decreased and Harris scores of stage II increased before and after treatment, P<0.05. The blood flow signal of the medial circumflex femoral artery of the femoral head could be detected in 20 of the 30 patients, includingⅠperiod 13 cases and Ⅱperiod 7 cases. Compared with that before the treatment, RI of medial rotated femoral artery decreased at the same stage, P<0.05. The percentage of femoral head necrosis in femoral head volume was lower after the same stage of treatment than that before the treatment, P<0.05. Compared with that of stage I, the percentage of femoral osteonecrosis volume in stage II increased before and after the treatment, P<0.01.Conclusion Triple therapy for the treatment of early adult femoral head necrosis has clinical curative effect, which was better in Ⅰ period than in Ⅱ period, so it has great clinical application value.
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Received: 04 July 2020
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