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Correlation between electrolyte changes and postoperative death in 320 patients with cerebral contusion |
CUI Shouyong1, ZHOU Cuiling2, MA Huili1, LI Mintao1,* |
1 Emergency Surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong, P.R.China; 2 Thoracic surgery, Binzhou Medical University Hospital, Binzhou 256603, Shandong, P.R.China |
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Abstract Objective To investigate the electrolyte changes in patients with cerebral contusion and analyze the risk factors of postoperative death.Methods Three hundred and twenty adult patients with cerebral contusion who required emergency craniotomy were enrolled in our hospital from November 2017 to October 2019. They were divided into three groups according to GCS scale at admission (mild group, medium group and severe group). The types of electrolyte disorders at the time of admission and within 24 hours after operation were analyzed, and the mortality was recorded. Multivariate logistic regression was used to analyze the risk factors of electrolyte disorders and mortality.Results Patients with cerebral contusion were more common in men; hypokalemia was common before operation (65.63%, 210/320), with an average of (3.27±0.91) mmol/L. Acidosis was common after operation (67.81%, 217/320), with an average of (20.57±2.82) mmol/L. Logistic regression analysis showed that hypernatremia and acidosis were risk factors for increased mortality within 24 hours after operation. The risk degree was 20.241 (27.550-6.497) and 4.012 (2.921-1.023) respectively.Conclusion The most common types of electrolyte disorders before and after operation are hypokalemia and acidosis respectively in patients with cerebral contusion. Hypernatremia and acidosis significantly increase the mortality within 24 hours after operation during perioperative period.
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Received: 08 May 2020
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