滨州市孕妇碘营养状况调查及其对新生儿甲状腺功能的影响

doi:10.19739/j.cnki.issn1001-9510.2020.03.009

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Abstract Objective To investigate the effects of different iodine nutrition status on thyroid function in pregnant women and TSH levels in newborns.Methods Two hundred and eighty-four pregnant women were selected in the third trimester of pregnancy (≥28 weeks of pregnancy) of a hospital in 2019.The morning-urine was collected to detect the levels of free triiodothyronine (FT₃), free thyroxine (FT₄) and sensitive thyroid stimulating hormone(sTSH).The venous blood samples were collected to detect the content of iodine in urine,chemiluminescencetthyroid peroxidase antibody (TPOAb) and thyro-globulin antibody (TGAb). Heel blood of 72 hours of normal term was collected to detect the levels of TSH.Results The ratios of urinary iodine in women in Binzhou area were below 149 μg/L, 150～249 μg/L, 250～499 μg/L, and above 500 μg/L were 18.31%, 13.73%, 19.01%, and 48.94%, respectively. There were 41 pregnant women suffering from thyroid disease (14.44%), 25 pregnant women suffering from methylene chloride (8.80%), and 16 pregnant women suffering from hypothyroidism (5.63%).The neonatal heel blood TSH level was (2.95 ± 2.50) mIU / L and 15.32% of neonatal heel blood TSH was higher than 5mIU / L. There was no significant difference in heel heel blood TSH of newborns born by pregnant women with different levels of iodine nutrition (P>0.05).Conclusion The iodine deficiency and iodine excess problems of pregnant women in Binzhou area coexist. The proportion of pregnant women with iodine excess is high, and the TSH level of newborns is high. The iodine nutrition status of pregnant women can affect the iodine nutrition level of newborns.

Key words： pregnant women neonate iodine nutrition thyroid function

Received: 05 November 2019

PACS:

R714.7

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	Articles by authors
	ZHANG Guiqin
	WANG Feng
	WANG Xiuzhen
	ZHANG Xianjuan
	LI Xin
	LI Jinling

Cite this article:

ZHANG Guiqin,WANG Feng,WANG Xiuzhen, et al. Survey on iodine nutritional status of pregnant women and thyroid function of neonates in Binzhou[J]. 滨州医学院学报, 2020, 43(3): 194-197.

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http://manu58.magtech.com.cn/Jwk_bzyxy/EN/10.19739/j.cnki.issn1001-9510.2020.03.009 OR http://manu58.magtech.com.cn/Jwk_bzyxy/EN/Y2020/V43/I3/194

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