胱抑素C与脑梗死、颈动脉粥样硬化斑块的相关性

doi:10.19739/j.cnki.issn1001-9510.2021.02.008

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Abstract Objective To investigate the correlation between serum cystatin C (CysC) levels and cerebral infarction and carotid atherosclerosis.Methods Three hundred and nineteen patients with cerebral infarction in our hospital were selected as the experimental group and 323 healthy physical examinees as the control group, and Carotid ultrasound was performed on all patients. According to the results of carotid ultrasound, the patients were divided into the plaque group and the non-plaque group. The clinical data of the two groups were compared, and the risk factors of cerebral infarction and plaque formation were analyzed by logistic regression.Results Age, CYS-C level and plaque detection rate in the experimental group were significantly higher than those in the control group, P<0.05. Age, CYS-C and carotid artery plaque were independent risk factors for cerebral infarction, P<0.05. The average age, number of smokers and cYS-C level in the plaque group were higher than those in the non-plaque group, P<0.05. Smoking and CYS-C levels were independent risk factors for carotid plaque formation, P<0.05.Conclusion The level of cystatin C is closely related to the formation of cerebral infarction and carotid artery plaque. Smoking cessation and control of cystatin C level can prevent the formation of carotid artery plaque, and it is of clinical significance to further prevent the occurrence of cerebral infarction.

Key words： cystatin C cerebral infarction carotid atherosclerosis

Received: 19 June 2020

PACS:

R743.1

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	Articles by authors
	WANG Jing
	XING Mengyang
	SUN Jian

Cite this article:

WANG Jing,XING Mengyang,SUN Jian. Correlation between cystatin C and cerebral infarction and carotid atherosclerotic plaque[J]. 滨州医学院学报, 2021, 44(2): 112-115.

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http://manu58.magtech.com.cn/Jwk_bzyxy/EN/10.19739/j.cnki.issn1001-9510.2021.02.008 OR http://manu58.magtech.com.cn/Jwk_bzyxy/EN/Y2021/V44/I2/112

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