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Comparative study of multimodal magnetic resonance imaging and ultrasonography in evaluating the diagnosis staging and radiotherapy effects of cervical cancer |
LI Yingna1, WANG Dongbing2, WANG Weiqing2, WU Xia2 |
1 Department of Ultrasound Imaging, Linyi Third People′s Hospital, Linyi 276023, Shandong,P.R. China; 2 Department of Oncology, Linyi Third People′s Hospital, Linyi 276023, Shandong, P.R. China |
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Abstract Objective To explore the comparative study of multimodal magnetic resonance imaging and ultrasonography in the diagnosis of cervical cancer and the efficacy of radiotherapy.Methods Totally 396 patients with cervical carcinoma who received assessment by multimodal MRI or color Doppler ultrasonography in The Third People′s Hospital of Linyi from October 2015 to October 2018 were recruited in this study. They were the multi-modality MRI group (n=201 ) and the color Doppler ultrasound inspection group (n=195 ). The results were analyzed and compared. The multi-modal MRI findings of cervical cancer before and after treatment were compared, and the effect of enhancement on multimodal magnetic resonance imaging was evaluated.Results The diagnostic coincidence rate of multi-modality MRI in detecting stage I and stage II cervical cancer was higher than that of color Doppler ultrasound (P<0.05), but there was no significant difference between the diagnostic coincidence rate of stage III and stage IV. The overall sensitivity of multi-modality MRI to evaluate the staging of cervical carcinoma was 94.6% and specificity was 92.8%. The overall sensitivity of color Doppler ultrasonography was 83.4% and specificity was 82.6%. There was a significant difference between the two (P<0.05). In roc curve analysis, the area of the multi-modal MRI curve was significantly larger than that of color Doppler ultrasonography, and the sensitivity and specificity were significantly higher than that of color Doppler ultrasonography (P<0.05). The accuracy of CR and PR in the evaluation of radiotherapy efficacy in patients with cervicalcancer by multi-modal MRI were lower than that of color Doppler ultrasonography (P<0.05). The enhancement of multi-modal MRI examination was significantly correlated with the evaluation of tumor reduction rate (r=0.649, P<0.01) and radiotherapy effect (r= 0.679, P<0.01). Comparing the multi-modal MRI findings of cervical cancer before and after treatment, it was found that multi-modal MRI could clearly show the size of the tumor and its relationship with the surrounding tissues and organs, and the lesions disappeared after radiotherapy.Conclusion Compared with color Doppler ultrasound, multi-modality MRI is of great value in the accurate diagnosis and staging of cervical cancer and provides a strong basis for the evaluation of radiotherapy effect of cervical cancer.
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Received: 06 March 2020
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