linc00673在结直肠癌患者血浆中的表达及临床意义

doi:10.19739/j.cnki.issn1001-9510.2020.03.011

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Abstract Objective To detect the expression of linc00673 in patients with colorectal cancer, and then explore the relationship between the expression of plasma linc00673 and clinical symptoms.Methods Totally108 hospitalized patients with colon polyps and colorectal cancer admitted to Shenzhen People's Hospital were enrolled. Real-time PCR was used to detect the difference in the expression of linc00673 in plasma of colorectal cancer and rectal polyps. The correlation between linc00673 and patient age, gender, TNM tumor stage, tumor location, gross type and lymph node metastasis and tumor volume was analyzed.Results Linc00673 was highly expressed in colorectal cancer tissues(P<0.05). Correlation analysis showed that high expression of linc00673 was not associated with age, gender, TNM tumor stage, tumor location, gross type and lymph node metastasis, and was positively correlated with tumor volume (P<0.01).Conclusion The high expression of linc00673 in colorectal cancer tissues suggests that linc00673 may be a potential marker for the diagnosis of colorectal cancer, which may provide a theoretical basis for the diagnosis and targeted therapy of colorectal cancer.

Key words： colorectal cancer plasma linc00673 diagnostic marker

Received: 28 October 2019

PACS:

R735.3

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	Articles by authors
	ZHANG Shipai
	LI Junyu
	ZOU Xiaohong
	HUANG Kaibin
	ZHONG Simei
	FU Yuxiang
	XIA Ligang

Cite this article:

ZHANG Shipai,LI Junyu,ZOU Xiaohong, et al. The expression and correlation analysis of linc00673 in plasma of patients with colorectal cancer between clinical features[J]. 滨州医学院学报, 2020, 43(3): 202-205.

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http://manu58.magtech.com.cn/Jwk_bzyxy/EN/10.19739/j.cnki.issn1001-9510.2020.03.011 OR http://manu58.magtech.com.cn/Jwk_bzyxy/EN/Y2020/V43/I3/202

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