[1] Jasti J, Furukawa H, Gonzales E B, et al. Structure of acid-sensing ion channel 1 at 1.9 resolution and low pH[J].Nature, 2007,449(7160):316-323. [2] Yang H, Yu Y, Li W G, et al. Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism[J].Plos Biology, 2009,7(7):e1000151. [3] Chai S, Li M, Branigan D, et al. Activation of acid-sensing ion channel 1a (ASIC1a) by surface trafficking[J]. J Biol Chem, 2010,285(17):13002-13011. [4] Vergo S, Craner M J, Etzensperger R, et al. Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model[J].Brain, 2011,134(Pt 2):571-584. [5] Xiong Z G, Zhu X M, Chu X P, et al. Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels[J].Cell, 2004,118(6):687-698. [6] Johnson M B, Jin K, Minami M, et al. Global ischemia induces expression of acid-sensing ion channel 2a in rat brain[J]. J Cereb Blood Flow Metab, 2001,21(6):734-740. [7] Li M, Kratzer E, Inoue K, et al. Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons[J].J Physiol, 2010,588(20):3883-3900. [8] Askwith C C, Wemmie J A, Price M P, et al. Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons[J]. J Biol Chem, 2004,279(18):18296-18305. [9] Yermolaieva O, Leonard A S, Schnizler M K, et al. Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a[J].Proc Natl Acad Sci U S A, 2004,101(17):6752-6757. [10] Wang Y Z, Zeng W Z, Xiao X, et al.Intracellular ASIC1a regulates mitochondrial permeability transition-dependent neuronal death[J]. Cell Death Differ, 2013,20(10):1359-1369. [11] Miesenb ck G, De Angelis D A, Rothman J E. Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins[J].Nature,1998,394(6689):192-195. [12] Wemmie J A, Chen J, Askwith C C, et al. The Acid-Activated Ion Channel ASIC Contributes to Synaptic Plasticity, Learning, and Memory[J].Neuron, 2002,34(3):463-477. [13] Gao J, Duan B, Wang D G, et al. Coupling between NMDA Receptor and Acid-Sensing Ion Channel Contributes to Ischemic Neuronal Death[J].Neuron, 2005,48(4):635-646. [14] Gao S, Yu Y, Ma Z Y, et al. NMDAR-Mediated Hippocampal Neuronal Death is Exacerbated by Activities of ASIC1a[J].Neurotox Res, 2015,28(2):122-137. [15] Allen N J, David A. Modulation of ASIC channels in rat cerebellar Purkinje neurons by ischaemia-related signals[J]. J Physiol, 2010,543(2):521-529. [16] Escoubas P, Bernard C, Lambeau G, et al. Recombinant production and solution structure of PcTx1, the specific peptide inhibitor of ASIC1a proton-gated cation channels[J]. Protein Sci, 2010,12(7):1332-1343. [17] Gu L, Yang Y, Sun Y, et al. Puerarin inhibits acid-sensing ion channels and protects against neuron death induced by acidosis[J].Planta Med, 2009,76(6):583-588. [18] Zhang Y, Zhou L, Zhang X, et al.Ginsenoside-Rd attenuates TRPM7 and ASIC1a but promotes ASIC2a expression in rats after focal cerebral ischemia[J].Neurol Sci,2012,33(5):1125-1131. [19] Yifeng M, Bin W, Weiqiao Z, et al. Neuroprotective effect of sophocarpine against transient focal cerebral ischemia via down-regulation of the acid-sensing ion channel 1 in rats[J]. Brain Res, 2011,1382(9):245-251. [20] Waldmann R, Champigny G, Bassilana F, et al. A proton-gated cation channel involved in acid-sensing[J]. Nature, 1997, 386(6621):173-177. |