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| Study on the effects of hawthorn proanthocyanidins on anti-oxidation,removing nitrite and inhibiting nitrosamine synthesis |
| MI Wei1, HAN Lizhen2, HAN Fulei1, ZHANG Hongping1, JIANG Wei1, LI Wenyang1, YANG Linghua1, HUANG Xuzhao1, TIAN Lijun3 |
1 Nutrition and Food Hygiene Section,Binzhou Medical University,Yantai 264003,P.R.China;
2 Oncology Department,Linyi People's Hospital;
3 Oncology Department, Binzhou Medical University Hospital |
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Abstract Objective To study the effects of hawthorn procyanidins (HPC) on anti-oxidation, removing nitrite,and blocking the synthesis of nitrosamines.Methods HPC and vitamin C concentrations were 20mg / L,80mg / L,140mg / L,200mg /L, 260mg /L, 320mg /L.Spectrophotometer was used in the HPC group to measure the ability to remove superoxide anion radicals(O-2·), hydroxyl radicals(·OH),and DPPH·,the ability of total antioxidant capacity,and the ability to remove nitrite and block nitrosamine synthesis, and the Results were compared between the two groups.Results The hydroxyl free radical(·OH)scavenging rate of HPC group was significantly higher than that of vitamin C group (P＜0.05) in the concentration range from 20mg/L to 260 mg/L.Under the setting concentration range,the DPPH free radical scavenging and total antioxidant capacity of HPC group were higher than those of vitamin C group (P＜0.05),And its free radical scavenging capacity and total antioxidant capacity were proportional to the concentration.HPC showed strong scavenging capacity against nitrite, and the scavenging capacity increased with the increasing concentration in the range of test concentration. In the range from 140mg/L to 320 mg/L, the scavenging rate of HPC for nitrite was higher than that of vitamin C group (P＜0.05).Conclusion HPC has a strong anti-oxidant effect, can effectively remove nitrite and block the synthesis of nitrosamines, and has a positive effect on the body's anti-aging and cancer prevention.
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Received: 08 August 2018
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