人参皂苷CK对重症急性胰腺炎大鼠肝功能和免疫作用的影响

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Abstract Objective To study the effect of the ginsenoside compound K(CK) on the function of liver and immunity in rats with severe acute pancreatitis(SAP).Methods Twenty-three rats with severe acute pancreatitis were treated by ginsenoside CK as the experimental group and 23 rats in the control group received normal SAP treatment.The changes of liver function indexes (AST,ALT,GGT and ALB) and immunity function indexes such as T cell (CD₃,CD₄,CD₈ cell and CD₄/CD₈ ) after the SAP rats received treatment in 3 days and 7days were determined.Results Compared with the control group, the plasma liver function index (AST,ALT, GGT,ALB and STB) levels and the immunity T cell function index(CD₃,CD₄,CD₈ cell and CD₄/CD₈)levels were increased in 3 days and 7 days and there was significant difference (P＜0.05).Conclusion Ginsenoside CK therapy can effectively protect the function of the liver and immunity in rats with severe acute pancreatitis, and also improve their overall condition.It was an important auxiliary treatment for SAP rats, and it’s worthy of deep research in the future.

Key words： ginsenoside compound K severe acute pancreatitis liver function immunity

Received: 14 March 2018

PACS:

R657.5

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	Articles by authors
	WANG Qinghua
	SHANG Qiongqiong
	ZHANG Jianmin
	QU Guiwu

Cite this article:

WANG Qinghua,SHANG Qiongqiong,ZHANG Jianmin, et al. Study of ginsenoside compound K on the effect of immunity and liver function in rats with severe acute pancreatitis[J]. 滨州医学院学报, 2018, 41(4): 241-243.

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http://manu58.magtech.com.cn/Jwk_bzyxy/EN/ OR http://manu58.magtech.com.cn/Jwk_bzyxy/EN/Y2018/V41/I4/241

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