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The therapeutic effect of Roux-en-Y radical gastrectomy combined with gastric bypass surgery on gastric cancer with diabetes mellitus |
SUN Qinglei1, LI Yuming1, JIANG Hong1, JIN Yongjun2, WU Fengjie1, YU Xingquan1, SONG Bingtan1, LI Hesheng1 |
1 Department of Gastrointestinal Surgery,Binzhou Medical University Hospital,Binzhou 256603,P.R.China; 2 Department of Endocrinology,Binzhou Medical University Hospital |
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Abstract Objective To investigate the therapeutic effect of Roux-en-Y radical gastrectomy combined with gastric bypass surgery on gastric cancer with diabetes mellitus.Methods Clinical data of 60 gastric cancer patients with type 2 diabetes mellitus was retrospectively analyzed.The patients were randomly divided into two groups,one group received conventional Roux-en-Y gastric cancer radical operation and the other group Roux-en-Y radical gastrectomy combined with gastric bypass surgery. The postoperative complications,postoperative Length of stay,fasting plasma glucose (FBG) ,2 hours postprandial blood glucose (2hPG) ,Insulin resistance index (HOMA-IR) were tested 1 day before operation and 1 month after operation.Results The two groups of operations were performed successfully with postoperative 10~21 d of hospital stay, all patients recovered well with good status of diet. No severe postoperative complications were found in all patients.The FPG,2 hPG of the group with Roux-en-Y Radical Gastrectomy Combined with Gastric Bypass surgery decreased significantly better than the other group form 1 day before operation to 1 month after surgery, also the insulin sensitivity index of the combined operation group was more obvious improvement, while the patients were no significant difference in body weight loss before and after surgery.The quality of life of all the patients is very well.Conclusion The complication of the Roux-en-Y radical gastrectomy combined with gastric bypass surgery does not increase, this combined operation has no effect on the radical area of gastric cancer, and the patient's diabetes disease improves greatly after the operation. It should to be a more suitable surgical treatment on gastric cancer combined with Type 2 diabetes.
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Received: 01 January 2018
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