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| The 5-Year survival rate of patients with pregnancy-associated breast cancer after therapeutic termination of pregnancy:a Meta-analysisWANG Hong LIU Kuikui WANG Hui |
| WANG Hong, LIU Kuikui, WANG Hui |
| Teaching and Research Section of Adult Nursing,School of Nursing,Binzhou Medical University,Yantai 264003,P.R.China |
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Abstract Objective To evaluate the 5-year survival rate of patients with pregnancy-associated breast cancer after therapeutic termination of pregnancy compared with those who continued the gestation,so as to provide an evidence for clinical practice.Methods This project utilized meta-analysis.Computer and manual retrieval was conducted to search literatures on cohort studies comparing the two methods of treatment.RevMan 5.3 software was used for statistical analyses.Results 5 cohort studies were retrieved out. Meta-analyses showed that there was no significant difference between the two methods[RR=1.00,95% CI(0.69～1.45),P=0.99＞0.05].Subgroup analysis by TNM staging showed no significant difference,either.In StageⅠ,RR was 0.99, with 95% CI(0.55～1.76),and P was 0.83. In StageⅡand Ⅲ,[RR 0.95,95% CI(0.46～1.95),P=0.62] and[RR 0.88,95% CI(0.25～3.10),P=0.67],respectively.Conclusion Termination of pregnancy demonstrated no significant improvement for the prognosis of the patients with pregnancy-associated breast cancer.While, more large-sample cohort studies are needed to confirm the conclusion.
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Received: 30 November 2016
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[1] DiFronzo L A,O'Connell T X.Breast cancer in pregnancy and lactation[J].Surg Clin North Am,1996,76(2):267-278.
[2] Wallack M K,Wolf J A,Bedwinek J,et al.Gestational carcinoma of the female breast[J].Curr Probl Cancer,1983,7(9):1-58.
[3] Andersson T M,Johansson A L,Hsieh C C,et al.Increasing incidence of pregnancy-associated breast cancer in Sweden[J].Obstet Gynecol,2009,114(3):568-572.
[4] Wells G A,Shea B J,O'Connell D,et al.The Newcastle-Ottawa Scale (NOS) for assessing the quality of non-randomized studies in Meta-analysis[J].Applied Engineering in Agriculture,2014,18(6):727-734.
[5] Rissanen P.Carcinoma of the breast during pregnancy and lactation[J].Br J Cancer,1968,22(4):663-668.
[6] 吴斌,魏仁志,王元正,等.妊娠期乳腺癌13例的治疗[J].肿瘤防治杂志,2002,9(1):82-83.
[7] 孙清慧,郭峰,任立军.妊娠相关乳腺癌20例诊治分析[J].疑难病杂志,2008,7(10):616-617.
[8] 张娟,周庆丰,李青峰, 等. 妊娠期乳腺癌24例临床分析[J].中国肿瘤临床与康复,2009,12(6):560-561.
[9] 陈国际,邵永孚,余宏迢.妊娠期及哺乳期乳腺癌的治疗和预后因素分析[J].实用癌症杂志,1999,15(1):42-44.
[10] 白兰.CYP2C19基因多态性对服用他莫西芬乳腺癌患者生存率暴响的系统评价[D].昆明医科大学,2015.
[11] Nugent P, O'Connell T.Breast cancer and pregnancy[J].Arch Surg,1985,120(11):1221-1224.
[12] Litton J K,Theriault R L.Breast cancer and pregnancy:current concepts in diagnosis and treatment[J].Oncologist,2010,15(12):1238-1247. |
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