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| Effect of costal perichondrium on reconstruction of mandibular condyle with Costochondral grafts |
| DONG Pengfei1, LI Guohua1, WANG Fang2, WANG Yuliang3 |
1 Department of Stomatology,Weihai Municipal Hospital,Weihai 264200,P.R.China;
2 Department of Oral and Maxillofacial Surgery, Binzhou Medical University Hospital;
3 Department of Oral and Maxillofacial Surgery,Yantai Affiliated Hospital of Binzhou Medical University |
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Abstract Objective To explore the mechanism about costal perichondrium regulating reconstruction of Costal Cartilage by observing the histological expressions and expressions of BMP-2 of the Costal Cartilage.Methods Rabbits were devided randomly into the experiment group and the control group.For the experiment group,costal perichondrium was protected in the operation of Costochondral reconstruction of mandibular condyles, while for the control group, costal perichondrium was removed.Histological observation and immunohistochemics were used to detect the histological changes and expressions of BMP-2 during different stages.Results Histological observation showed that the proliferation of the chondrocytes in the experiment group happened earlyer than that in the control group.The expressions of BMP-2 of the Costal Cartilage showed that there was more positive results in the experiment group,with statistical significance.Conclusion Costal perichondrium has a beneficial function in regulating proliferation and reconstructing Cartilage.
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Received: 02 April 2017
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