|
|
|
| Value of CHA2DS2-VASc score in the differential diagnosis of cardioembolic transient ischemic attack |
| WANG Yuan, MA Wenbin, Wang Meiling, LI Xizhi, LI Mingyuan* |
| Department of Neurology, Binzhou Medical University Hospital, Binzhou 256603, Shandong, P. R. China |
|
|
|
|
Abstract Objective To explore CHA2DS2-VASc score and ABCD2 score values in differential diagnosis of cardiogenic transient ischemic attack (TIA).Methods Clinical data and ABCD2, CHA2DS2-VASC score results of 60 patients with clinically confirmed cardiogenic TIA (group A) and non-cardiogenic TIA (group B) were reviewed and compared.Results There were no significant differences in baseline characteristics between the two groups, such as gender, age, associated onset and duration, clinical symptoms, and previous history of stroke, but there were significant differences in CHA2DS2-VASc scores (t=2.70, P<0.05), and the area under the ROC curve of the CHA2DS2-VASC score for the diagnosis of cardiogenic TIA was 0.682 (95%CI: 0.526-0.837, P<0.05).Conclusion CHA2DS2-VASC score can be used as a reference index in the actual management of clinical TIA to help identify the possibility of cardiogenic TIA, so as to guide early intervention in hospitals.
|
|
Received: 10 September 2020
|
|
|
|
|
|
[1] 龚涛,王新德.72例短暂性脑缺血发作患者第四次长期随访[J].中华老年医学杂志,2001,20:85-88.
[2] CHANDRATHEVA A, MEHTA Z, GERAGHTY O C, et al. Population-based study of risk and predictors of stroke in the first few hours after a TIA[J]. Neurology, 2009, 72: 1941-1947.
[3] 祁智慧,刘北京,宋建华.低分子肝素钙治疗短暂性脑缺血发作46例临床观察[J].滨州医学院学报,2002,25(1):60.
[4] WOLF P A, ABBOTT R D, KANNEL W B, et al. Atrial fibrillation as an indepent risk factor for stroke:a framingham study[J]. Stroke, 1991, 22:983-988.
[5] LIN S, WU B, HAO Z L, et al. Characteristics, treatment and outcome of ischemic stroke with atrial fibrillation in a Chinese hospital-based stroke study[J]. Cerebrovasc Dis, 2011, 31:419-426.
[6] KIMURA K, MINEMATSU K, WADA K, et al. Clinical characteristics in transient ischemic attack patients with atrial fibrillation[J]. Intern Med, 2003, 42:255-258.
[7] LUCIANO A S, SPOSATO L E, SAPOSNIR G, et al. Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis[J]. Lancet Neurology, 2015,14(4):377-387.
[8] 郭雨竹,邢英琦.对比增强经颅多普勒超声诊断右向左分流相关问题探讨[J].中国卒中杂志,2016,11(7):515-529.
[9] 刘光平,陈桂华.脑血管疾病322例经颅多普勒检查分析[J].滨州医学院学报,1998,21(2):154-155.
[10] MANGIAFICO S, SCANDURA S, USSIA G P, et al. Transesophageal echocardiography and transcranial color-Doppler: independent or complementary diagnostic tests for cardiologists in the detection of patent foramen ovale[J]. Cardiovascular Med(Hagerstown),2009,10(2):143-148.
[11] MITCHELL L B, SOUTHERN D A, GALBRAITH D, et al. Prediction of stroke or TIA in patients without atrial fibrillation using CHADS2 and CHA2DS2-VASc scores[J]. Heart, 2014, 100:1524-1530.
[12] KIM T H, SHIM C Y, PARK J H, et al. Left ventricular diastolic dysfunction is associated with atrial remodeling and risk or presence of stroke in patients with paroxysmal atrial fibrillation[J]. Journal of Cardiology, 2016, 68:104-109.
[13] MILLER T R, GROSSMAN S J, SCHECTMAN K B, et al. Left ventricular diastolic filling and its association with age[J]. Am J Cardiol, 1986, 58: 531-535.
[14] CARLUCCIO E, BIAGIOLI P, ALUNNI G, et al. Effect of revascularizing viable myocardium on left ventricular diastolic function in patients with ischaemic cardiomyopathy[J]. Eur Heart J, 2009, 30: 1501-1509.
[15] 英硕,万征,杜鑫,等.左室舒张功能不全对非瓣膜性PAF患者左心耳血栓形成的影响[J].山东医药,2013,53:57-59.
[16] 陈梦佳,PETER NORDBECK, 胡凯,等.左心室血栓形成的危险因素及预后意义[J].中华心血管病杂志,2018,46:516.
[17] 樊燕琴,杨清,韩红亚,等.高龄老年心房颤动患者临床特征及诱因分析[J].心肺血管病杂志,2016,35(9):715-718.
[18] LI S Y, ZHAO X Q, WANG C X, et al. One-year clinical prediction in Chinese ischemic stroke patients using the CHADS2 and CHA2DS2-VASc scores: the China National Stroke Registry[J]. Cns Neuroscience & Therapeutics, 2012, 18(12):988-993. |
|
|
|
