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Correlation between bone density T value and coronary heart disease in the elderly |
WANG Yuanyuan, CUI Jianguo, QI Jie, CHANG Jiyang, ZHANG Qingtan* |
Department of Geriatrics, Binzhou Medical University Hospital, Binzhou 256603, Shandong, P.R.China |
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Abstract Objective To investigate the correlation between bone mineral density T value and coronary heart disease in the elderly.Methods Retrospective analysis was performed on 512 elderly patients who underwent coronary angiography and bone mineral density examination.According to the results of coronary angiography, 273 patients in the coronary heart disease group and 239 patients in the non-coronary heart disease group. According to the results of DXA bone mineral density examination, there were 302 cases of low bone density group and 210 cases of normal bone density group. The general conditions of each group of patients, the difference of laboratory test indicators, and bone density T value were compared. Logistic regression analysis was used to analyze the risk factors of coronary heart disease in the elderly.Results In 512 elderly patients, the T-value of bone density was lower in the coronary heart disease group and the risk of low bone mineral density was higher in the non-coronary heart disease group (P<0.05 or<0.01). Compared with the normal bone density group, the group with low bone mineral density had the high proportion of older, female and diabetic patients, the T-value of bone mineral density was lower, and uric acid was higher (P<0.05 or<0.01). Correlation analysis showed that the bone density T value was negatively correlated with age, ALP, FBG (P<0.01), the bone density T value was positively correlated with uric acid (P<0.001). Regression analysis showed that aging, diabetes, were risk factors for low bone density. The results of single factor and multivariate logistic regression analysis showed that high bone density T value was an independent risk factor for coronary heart disease (P<0.05). Conclusion Low bone density T value is an independent risk factor for the onset of coronary heart disease in the elderly.
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Received: 18 December 2019
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